63 research outputs found

    Data-Driven Decision Making as a Model to Improve in Primary Education

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    The digital evaluation field is a new area that arises in the core of education and studies highlight the importance of editing data as well as using ICT to drive internal school improvement. Data- Driven Decision Making (DDDM in advance) executes relatively simple models on carefully targeted data extracted through target questionnaires. This article contributes to the creation of a DDDM plan that considers the evaluation of a primary school in Greece. The research design is based on the DigCompOrg model and uses a quantitative technique through a questionnaire. The results presented include the analysis of the teaching team. Extracted data enabled the researchers to identify the requirements that the specific school must meet in order to proceed with self-evaluation in its digitalization process. The percentage results for teachers’ self-perception of ICT use in lessons, teachers’ digital competence, digital content use, pedagogical evaluation, digital communication with parents and digital support of school leadership indicated that significant changes in ICT integration continue to occur in the specific primary school, ICT culture and most of its components. For these reasons, this article presents a proposal for a DDDM theoretical model plan for primary school improvement presented at the end

    Altruism and information

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    Experimental literature has accumulated evidence on the association of personal characteristics to a higher or lower level of prosocial behavior. There is also evidence that donations are affected by the mere provision of information about the recipients, whatever its nature or content. In this paper, we present a unified experimental framework to analyze the impact of social class, political orientation and gender on the level of giving; our experimental design allows us to reveal the effect of providing information by itself, with respect to the baseline treatment of no information, and separately from the effect of the informational content. These results could be relevant to any design intended to measure the impact on altruism of different manipulations of the Dictator Game

    Cursos online masivos en abierto: caso de estudio longitudinal

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    Este trabajo parte de una revisión teórica sobre los MOOC y sus características, además de un análisis de estadísticas recientes que muestran la relevancia del fenómeno y a la par las altas tasas de deserción que se producen. A partir de esta revisión, nuestro trabajo se centra en el análisis de un caso: el MOOC "Educación en un mundo conectado" impartido por el GITE de la Universidad de Murcia a través de la plataforma Canvas en 2015 y con 2500 usuarios inscritos. El objetivo del estudio es profundizar en las razones por las cuales los alumnos se interesan por un MOOC y analizar la experiencia de un caso de estudio longitudinal. La recogida de información se ha realizado con la técnica de encuesta a través de cuestionarios implementados en diversas fases del MOOC (inicial, de proceso y final). Aunque en este MOOC la participación ha sido alta y los índices de deserción han quedado por debajo de los habituales en los MOOC, hemos encontrado algunos aspectos del curso susceptibles de mejora, siendo sobre todo la interactividad con el profesorado la mayor debilidad encontrada por parte de los alumnos

    Altruism and information

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    Experimental literature has accumulated evidence on the association of personal characteristics to a higher or lower level of prosocial behavior. There is also evidence that donations are affected by the mere provision of information about the recipients, whatever its nature or content. In this paper, we present a unified experimental framework to analyze the impact of social class, political orientation and gender on the level of giving; our experimental design allows us to reveal the effect of providing information by itself, with respect to the baseline treatment of no information, and separately from the effect of the informational content. These results could be relevant to any design intended to measure the impact on altruism of different manipulations of the Dictator Game

    Estudio comparativo de la influencia de la posicion de trabajo en las franjas clinicas de los alumnos de la carrera de Kinesiologia y Odontologia de la Universidad de Talca y su relacion con alteraciones musculoesqueleticas

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    98 p.El propósito de este estudio es realizar un estudio comparativo de la influencia de las posiciones de trabajo en las franjas clínicas de los alumnos de Kinesiología y Odontología de la Universidad de Talca. Se evaluó a 155 alumnos de la carrera de Kinesiología y 191 alumnos de la carrera de Odontología de la Universidad de Talca, considerando a todos los alumnos regulares que están cursando prácticas clínicas. Se le realizó una encuesta por nivel de educación a los alumnos, que consiste en 16 preguntas, las que fueron contestadas en un periodo de tiempo que no superó los 5 minutos. Una vez que se obtuvieron los datos fueron tabulados y evaluados mediante el sistema Microsoft Office Excel. Los datos fueron analizados por nivel de educación, estableciéndose las principales comparaciones por nivel y un análisis de la carrera en general para establecer conclusiones representativas para cada carrera. Se estableció el patrón postural para la carrera de Kinesiología como la posición de píe dinámica y para la carrera de Odontología la posición sedente en silla utilizando respaldo. Realizando una asociación entre las posiciones adoptadas en el trabajo clínico y las alteraciones músculo esqueléticas más frecuentes, se concluyó que los síntomas principales en los alumnos de Kinesiología son los dolores músculo esqueléticos y la sensación de irritabilidad y para la carrera de Odontología son los dolores músculo esqueléticos y las cefaleas

    Análisis Conceptual de Modelos de Competencia Digital del Profesorado Universitario

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    La competencia digital o competencia TIC es un concepto que en el último lustro ha marcado una línea de investigación de gran relevancia en el ámbito de la Tecnología Educativa, tanto referido al profesorado como a otros agentes educativos o sociales. La perspectiva desde la cual abordamos el estudio de la competencia digital del profesorado parte de la idea de que esta competencia forma parte de la competencia profesional de los docentes de cualquier nivel de enseñanza. En este artículo realizamos una investigación basada en una revisión documental articulada en dos fases: 1) análisis conceptual de las aportaciones más relevantes del último lustro en torno a la competencia digital; y 2) a partir de este análisis, realizamos en una segunda fase un estudio descriptivo y comparativo de los diversos modelos de competencia digital del profesorado universitario. Este análisis pone de manifiesto que todos los modelos analizados muestran dimensiones y elementos comunes, pero también algunas particularidades que resultan de interés a la hora de abordar futuras investigaciones sobre el tema. Además nos servirá como punto de partida para una investigación en torno a la certificación de competencias TIC del profesorado universitario que actualmente estamos desarrollando desde el Grupo de Investigación de Tecnología Educativa de la Universidad de Murcia

    Beyond the ‘East-West’ dichotomy: global variation in cultural models of selfhood

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    Markus and Kitayama’s (1991) theory of independent and interdependent self-construals had a major influence on social, personality, and developmental psychology by highlighting the role of culture in psychological processes. However, research has relied excessively on contrasts between North American and East Asian samples, and commonly used self-report measures of independence and interdependence frequently fail to show predicted cultural differences. We revisited the conceptualization and measurement of independent and interdependent self-construals in 2 large-scale multinational surveys, using improved methods for cross-cultural research. We developed (Study 1: N = 2924 students in 16 nations) and validated across cultures (Study 2: N = 7279 adults from 55 cultural groups in 33 nations) a new 7-dimensional model of self-reported ways of being independent or interdependent. Patterns of global variation support some of Markus and Kitayama’s predictions, but a simple contrast between independence and interdependence does not adequately capture the diverse models of selfhood that prevail in different world regions. Cultural groups emphasize different ways of being both independent and interdependent, depending on individualism-collectivism, national socioeconomic development, and religious heritage. Our 7-dimensional model will allow future researchers to test more accurately the implications of cultural models of selfhood for psychological processes in diverse ecocultural contexts

    Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere’s Disease

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    Meniere’s disease (MD) is a rare disorder characterized by episodic vertigo, sensorineural hearing loss, tinnitus, and aural fullness. It is associated with a fluid imbalance between the secretion of endolymph in the cochlear duct and its reabsorption into the subarachnoid space, leading to an accumulation of endolymph in the inner ear. Epidemiological evidence, including familial aggregation, indicates a genetic contribution and a consistent association with autoimmune diseases (AD). We conducted a case–control study in two phases using an immune genotyping array in a total of 420 patients with bilateral MD and 1,630 controls. We have identified the first locus, at 6p21.33, suggesting an association with bilateral MD [meta-analysis leading signal rs4947296, OR = 2.089 (1.661–2.627); p = 1.39 × 10−09]. Gene expression profiles of homozygous genotype-selected peripheral blood mononuclear cells (PBMCs) demonstrated that this region is a trans-expression quantitative trait locus (eQTL) in PBMCs. Signaling analysis predicted several tumor necrosis factor-related pathways, the TWEAK/Fn14 pathway being the top candidate (p = 2.42 × 10−11). This pathway is involved in the modulation of inflammation in several human AD, including multiple sclerosis, systemic lupus erythematosus, or rheumatoid arthritis. In vitro studies with genotype-selected lymphoblastoid cells from patients with MD suggest that this trans-eQTL may regulate cellular proliferation in lymphoid cells through the TWEAK/Fn14 pathway by increasing the translation of NF-κB. Taken together; these findings suggest that the carriers of the risk genotype may develop an NF-κB-mediated inflammatory response in MD

    Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism

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    © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Whole-brain radiotherapy (WBRT) is the treatment backbone for many patients with brain metastasis; however, its efficacy in preventing disease progression and the associated toxicity have questioned the clinical impact of this approach and emphasized the need for alternative treatments. Given the limited therapeutic options available for these patients and the poor understanding of the molecular mechanisms underlying the resistance of metastatic lesions to WBRT, we sought to uncover actionable targets and biomarkers that could help to refine patient selection. Through an unbiased analysis of experimental in vivo models of brain metastasis resistant to WBRT, we identified activation of the S100A9-RAGE-NF-κB-JunB pathway in brain metastases as a potential mediator of resistance in this organ. Targeting this pathway genetically or pharmacologically was sufficient to revert the WBRT resistance and increase therapeutic benefits in vivo at lower doses of radiation. In patients with primary melanoma, lung or breast adenocarcinoma developing brain metastasis, endogenous S100A9 levels in brain lesions correlated with clinical response to WBRT and underscored the potential of S100A9 levels in the blood as a noninvasive biomarker. Collectively, we provide a molecular framework to personalize WBRT and improve its efficacy through combination with a radiosensitizer that balances therapeutic benefit and toxicity.info:eu-repo/semantics/publishedVersio
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